The COVID-19 pandemic[1] continues to impact the world profoundly and has had far-reaching consequences beyond health and disease outcomes in populations. Recognizing this pandemic’s complex, multi-faceted nature, READY has developed an integrated response framework to minimize COVID-19 transmission in vulnerable communities. By supporting the adherence to two selected non-pharmaceutical interventions (NPIs) through integrated multi-sectoral, holistic humanitarian services and designing an integrated response framework around specific NPIs, the framework promotes an integrated lens for outbreak readiness and response. This framework enables us to accomplish greater multi-sector cohesiveness, implement holistic service models, improve communications and coordination among various actors, maximize limited resources, minimize possible trade-offs, and promote more efficient ways of working.

While it is recommended that an effective COVID-19 response includes a comprehensive set of mitigation and containment interventions, this framework focuses primarily on enabling holistic services around a sub-set of common interventions: 1) Quarantine and isolation in the household, and 2) Quarantine Facilities and Community Isolation Centers. Quarantine and isolation are commonly used by national and local officials to reduce disease transmission. For example, to reduce transmission, the World Health Organization (WHO) recommends that individuals suspected or confirmed for COVID-19 should quarantine or isolate for up to two weeks. Asymptomatic individuals or individuals with mild to moderate symptoms can isolate at home. They may have to do so with household members who are also encouraged to quarantine. In low-resource settings, it is challenging to ensure these isolated and/or quarantined households have sufficient access to basic needs such as food and water, other essential services, and information. In particular, these households need to be protected from any increased vulnerabilities caused or made worse by isolation. Many of these services may be missing or delivered through vertical sectoral programming, which aligns funds, benchmarks, and technical expertise solely to one technical area. While recognizing that this framework does not include the full menu of possible mitigation and containment measures, its goal is to guide detailed planning and implementation around quarantine and isolation with hopes to expand and consider other interventions in the future iterations.

The framework, through desk research and consultations, has adapted several tools and approaches from agencies such as the WHO, Inter-Agency Standing Committee (IASC), Active Learning Network for Accountability and Performance (ALNAP), and from non-governmental organizations (NGOs) such as Save the Children, International Rescue Committee, and academic institutions such as the London School of Hygiene and Tropical Medicine and the Johns Hopkins University.

The Framework

This framework is intended for technical experts, country directors, program directors, program managers, and program staff of national and international NGOs to guide their organization’s strategy, proposal development, program implementation, and operational activities for the COVID-19 emergency response. By promoting holistic support to individuals with suspected or confirmed COVID-19 (who have been quarantined or isolated either in their households or at voluntary or involuntary facilities/centers), the framework aims to minimize transmission of COVID-19 in vulnerable communities through improved adherence to the two selected non-pharmaceutical interventions (NPIs).

The framework builds on a foundation of key principles and entry points for effective multi-sectoral integrated programming to accomplish this goal. These entry points are organized along the program cycle (Strategic Leadership and Coordination, Planning, Proposal Development & Project Design, Program Implementation, and Monitoring, Evaluation, Accountability & Learning (MEAL)). The design guides the process for enabling multiple sectors and cross-cutting areas to contribute to the same goals and objectives. The framework then aligns each sector, with considerations from the cross-cutting areas, to enable relevant activities and services to contribute to these common goals and objectives.

The framework brings together existing sector-specific technical and operational guidelines that have been developed by the humanitarian community, including guidelines from Health [Community Health Programming; Reproductive, Maternal, Newborn, Child and Adolescent Health (RMNCAH); and Mental Health and Psychological Support (MHPSS); Water, Sanitation, and Hygiene (WASH); Protection (Child Protection and Gender-Based Violence); Nutrition; and Food Security.

Cross-cutting themes relevant to all sectors need to be kept at the forefront of how outbreak responses are designed and implemented. These themes include Social and Behavior Change (SBC), specifically through Risk Communication and Community Engagement (RCCE), age, gender, ability, ethics, and OneHealth.

[1] Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the name given to the 2019 novel coronavirus. COVID-19 is the name given to the disease associated with the virus. To appeal to a wider audience, including non-health and entry-level program staff, this document will refer to programming in COVID-19.

What is integration?

Integrated programming holistically addresses the multiple and inter-related rights, needs, risks, and vulnerabilities of individuals and communities. An integrated approach ensures that interventions from different sectors and teams do not occur in isolation (i.e., siloed). Instead, these interventions will reinforce one another to achieve the best possible outcomes with existing resources.

Why is integrated programming important in response to COVID-19?

  • In locations with widespread community transmission or where access and movement are restricted, we must continue to maximize our resources to make the biggest collective impact across sectors and teams. Now more than ever, it is vital to adopt a collaborative approach.
  • Building on the existing structures within countries, governments, national and international organizations, coordination bodies, and communities enables us to pursue a coordinated response with a clear flow of information to support the service continuation, build trust, and meet community needs.
  • Adopting an integrated lens in this pandemic promotes efficient ways of working; thereby, enabling a more community-centered approach and greater care for frontline and aid workers. Simultaneously, this approach reinforces Do No Harm practices by ensuring a balance between public health guidance and protection principles, as well as through practical measures such as physical distancing and the consistent use of personal protective equipment (PPE).

What are Non-Pharmaceutical Interventions (NPIs)?

NPIs include all measures or actions, outside of vaccines or medicines, that can be implemented to prevent, slow the spread of, or treat, a communicable disease in a population.[2] NPIs are also known as community mitigation strategies. With no known vaccine or treatment for COVID-19, the most effective ways to reduce transmission and save lives are through:

  1. Personal NPIs, including hand-washing, respiratory hygiene, physical distancing, self-isolation, household quarantine, and protecting vulnerable individuals (such as the elderly) within the household.
  2. Environmental NPIs, including regular cleaning and disinfecting surfaces and ensuring ventilation in public buildings.
  3. Community NPIs, such as physical distancing, closure of schools and universities, the closing of non-essential businesses, and bans on mass gatherings.
  4. Containment Measures, including surveillance, testing, isolation, contact tracing, quarantine, and border measures, if needed.

How are household quarantine and household isolation defined?

In the context of COVID-19, the quarantine of contacts is the restriction of activities and/or the separation of persons who are not ill but who may have been exposed to an infected person.[3] The objective is to monitor their symptoms and ensure the early detection of cases. On the other hand, isolation is the separation of infected persons from others to prevent the virus’s spread.[4] At the household level, if a member of the household is suspected or confirmed to have COVID-19 and is either asymptomatic or has mild to moderate symptoms, they can isolate at home under certain conditions. Additionally, household members are encouraged, as high-risk contacts, to self-quarantine within the house to reduce the likelihood of transmission to the broader community.

How are quarantine facilities and community isolation centers defined?

In resource-restricted settings, such as refugee camps and crowded urban settings, it may be difficult for individuals to isolate or quarantine at home. In some cases, governments and local authorities are requiring facility-based isolation. Therefore, quarantine facilities and community isolation centers (CICs) are being set up to enable early detection and treatment referral. Quarantine facilities enable the separation of persons who have been in contact with someone suspected or confirmed to have COVID-19. Community isolation centers provide people with mild to moderate symptoms, who are not at increased risk for severe disease, with a safe space to voluntarily isolate until they are no longer considered infectious according to the respective country’s Ministry of Health guidelines.[5] It is essential to distinguish CICs from isolation treatment centers: CICs offer individuals with mild or moderate symptoms a voluntary option to isolate if they cannot do so in their homes. Isolation treatment centers are for individuals with severe symptoms requiring medical treatment and care. Both quarantine facilities and CICs will monitor the daily symptoms of those admitted, and the CIC staff refer people to isolation treatment centers if needed.

Quarantine facilities and community isolation centers should be voluntary spaces, although we recognize that this isn’t always the case, and some governments and local authorities are enforcing facility-based isolation and quarantine. We recognize the inherent risks and rights issues that exist with involuntary centers. This integrated framework is designed to identify and reduce those risks through holistic multi-sectoral support. This guidance does not advocate for establishing or implementing forced quarantine or isolation facilities, especially given the possible distress and family separation this may cause. The preference is always to have contacts self-quarantine at home. Additionally, contacts with suspected or confirmed cases, whether they are asymptomatic or with mild or moderate symptoms, should self-isolate at home. However, given contextual realities, this guidance seeks to offer recommendations to humanitarian actors to help them mitigate risks and provide best practices for offering holistic care to individuals in quarantine or CICs.

How did READY prioritize isolation and quarantine as the focus of this framework?

Through consultations with partners and country offices responding to the COVID-19 pandemic, READY determined that authorities would continue to prioritize physical distancing measures in the current context and for the immediate future, especially where case numbers are low and where there is a capacity for containment interventions in resource-constrained settings, such as refugee camps. In addition to consultations, READY conducted a scoring exercise to further narrow the type of NPI physical distancing. READY selected the most relevant NPIs for illustrating this framework. The criteria used for this exercise included:

  1. Evidence: Level of current evidence to support implementing the NPI.
  2. Applicability: The NPI is applicable in various geographical contexts where NGOs are implementing programs.
  3. Timing: The NPI will be directly applicable in the planning and response phases for COVID-19.
  4. Multi-sector Programming: Ability to demonstrate relevance and applicability of multi-sector programming (at least four sectors) to encourage and maintain adherence to the NPI.
  5. Contribute to Evidence: The potential to contribute to ongoing and future evidence of implementing these NPIs in a respiratory epidemic/pandemic.

[2]  Centers for Disease Control
[3]  International Health Regulations (2005) Third edition. 2016. Geneva: World Health Organization; 2020. Posted at, accessed August 26, 2020)
[4]  Considerations for Quarantine of Contacts of COVID-19 Cases. Interim Guidance. 2020. Geneva: World Health Organization; 2020. Posted at, accessed August 26, 2020)
[5]  Operational Guidelines for Community Isolation Centers for COVID-19 in Low Resource Settings. 2020. Centers for Disease Control and Prevention; 2020. Posted at, accessed August 26, 2020)


Full Expression


Accountability to Affected Populations


Active Learning Network for Accountability and Performance


Antenatal care


Anti-retroviral therapy


British Broadcasting Corporation


Basic Emergency Obstetric and Newborn Care


(USAID) Bureau for Humanitarian Assistance


Comprehensive Emergency Obstetric and Newborn Care


Community health assistant


Community health worker


Community isolation center


Isolation Treatment Center


Community-based management of acute malnutrition


Clinical management of rape


Child Protection


Child Safeguarding


Civil Society Organization


District Health Information Software


Department of Peace Operations


Emergency Food Security Program


WHO’s Early Warning, Alert and Response System


Food and Agriculture Organization


Famine Early Warning System Network

FOCUS 1000

Facilitating and Organizing Communities to Unite for Sustainable Development


Family Planning


Gender-Based Violence


Global Humanitarian Response Plan


GOAL International (not an acronym: GOAL is an international humanitarian response agency with its headquarters in Dublin, Ireland)


Inter-Agency Standing Committee


Interim care center


Information, Education, and Communication


International Federation of Red Cross and Red Crescent Societies


International non-governmental organization


Infection Prevention and Control


Intimate partner violence


Knowledge, Attitudes, and Practices


Lesbian, gay, bisexual, transgender, intersex, questioning


Lady health worker


Monitoring, Evaluation, Accountability, and Learning


Mental Health and Psychosocial Support


Multi-Sector Initial Rapid Assessment


Minimum Initial Services Package


Ministry of Health


Maximizing the Quality of Scaling Up Nutrition Plus


multi-sectoral nutrition action plan


Mid-Upper Arm Circumference


Non-governmental organization


Non-pharmaceutical intervention


Post-exposure prophylaxis


Postnatal care


Personal protective equipment


Post-partum hemmorhage


Preventing Sexual and Exploitation Abuse


Psycho-social support


Risk Communication and Community Engagement


READY is the complete name (not an acronym) of the initiative that produced this Integrated Framework (more at


Reproductive Health


Reproductive, Maternal, Newborn, Child and Adolescent Health


Ready-to-use therapeutic food


Social and Behavior Change


Social Mobilization Action Consortium


Simple Messaging Service (also called “text messaging” or “texting”)


Standard Operating Procedure


Sexual and Reproductive Health


Sexually transmitted infection


Scaling Up Nutrition


Technical Assistance


Traditional birth attendant


United Nations


United States Agency for International Development


Water, Sanitation, and Hygiene


World Food Programme


World Health Organization

Integrated programming holistically addresses the rights, needs, risks, and vulnerabilities of individuals and communities. By designing an integrated response framework for COVID-19, READY intends to promote an integrated lens for outbreak readiness and response. The framework enables READY to accomplish greater multi-sector cohesiveness, implement holistic service models, improve communications and coordination among various actors, maximize limited resources, minimize possible trade-offs, and promote more efficient ways of working. By adopting a socio-ecological model to address two key NPIs of (1) household quarantine and household isolation and (2) quarantine facilities and community isolation centers, READY proposes a way to simultaneously meet the essential needs of individuals and communities while adhering to these NPIs and reducing COVID-19 transmission.

The integration entry points maximize humanitarian agencies’ potential to deliver coordinated programming while maintaining standards and quality benchmarks specific to each sector. This guidance note further provides illustrative activities per key sector and technical area to demonstrate how to promote adherence to physical distancing NPIs, highlights cross-cutting themes across the sectors. Additionally, the guidance note provides examples of how various sectors need to adapt overall programming needs for COVID-19 responses.

As the COVID-19 response is ongoing and dynamic, this framework serves as preliminary guidance that will be updated with country-level experiences and practical suggestions to inform emergency readiness and response for future outbreaks.

This framework is made possible by the generous support of the American people through the United States Agency for International Development (USAID). The contents are the responsibility of the READY Consortium and do not necessarily reflect the views of USAID or the United States Government.

A download link to the .pdf version of the Integrated Framework will be available here shortly.